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Biochem.Psychopharm., Vol.18, 19:84, Raven Press, New York.īoduar, R. E., Rossier, J., Battemberg, F., and Ling, N., 1978, Beta-endorphin cellular localization and behavioral effects, Adv. D., 1978, Endomorphine, Beta-LPH and ACTH: biochemical, pharmacological and anatomical studies, ., 18:125.īloom, F. This process is experimental and the keywords may be updated as the learning algorithm improves.Īkil, H., Watson, J., Berger, T. These keywords were added by machine and not by the authors. Preliminary data would suggest interesting modifications of B-endorphins in peripheral blood during strong suggestions of pain in the hypnotic state. Plasmatic B-endorphin determination is performed by a radio-immunologic method after a chromatographic step (gel filtration or HPLC). The authors are studying normal and heroin addicted subjects. We have less information about the behavior of these neuropeptides during hypnosis under neutral, analgesic and painful suggestions and this is the field of our research. Owing to the difficulty of B-endorphin determination in biological fluids, the studies have supplied interesting but contradictory results. Diagnostic and clinical implications have been prospected in the pain field, and in relation with B-endorphins affinity with endogenous opiate receptor, in opiates addiction. The importance of B-endorphins and other polypetides has been demonstrated recently in the central modulation of pain and in analgesia.
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